Labial melanotic macule Citalopram Induced Oral Melanotic Macules in a Female Patient and a Review of the Literature Cureus Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in dermoscopy: A pigmented labial lesion Mucosal melanocytic macules Oral melanotic macules are harmless but can be removed easily with laser treatment! Quick, safe, and effective. Say hello to even toned lips! #laser #candela #pico #lips #face #makeup #spa