Mitochondrial glutathione redox cycle and interaction with other antioxidant MedLink Neurology Epicatechin ameliorative effects on methotrexate induced hepatotoxicity in mice Reza Azadnasab, Hadi Kalantar, Layasadat Khorsandi, Heibatullah Kalantari, Mohammad Javad Khodayar, 2021 Full article: L methionine protects against nephrotoxicity induced by methotrexate through modulation of redox status and inflammation Methotrexate Support Bundle Theralogix Targeted brain delivery of methotrexate by glutathione PEGylated liposomes: How can the formulation make a difference? ScienceDirect Leucovorin (Folinic Acid) The Rescue Drug! Pearl:Leucovorin (Folinic Acid) is Methotrexate's antidote. It is the reduced form of folate that can bypass the enzyme dihydrofolate reductase (which Methotrexate inhibits). Application: It