Pathology Outlines Melanotic macule Benign Melanocytic Neoplasms Plastic Surgery KeyPlastic Surgery Key Melanocytic neoplasms Plastic Surgery KeyPlastic Surgery Key Oral melanotic macule and primary oral malignant melanoma: Epidemiology, location involved, and clinical implications Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in a High power view of a melanotic macule (biopsy from 2004) with typical Download Scientific Diagram