Acetaminophen causes neurodevelopmental injury in susceptible babies and children: no valid rationale for controversy Paracetamol (Acetaminophen) and the Developing Brain Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Frontiers Paracetamol Induced Glutathione Consumption: Is There a Link With Severe COVID 19 Illness? Acetaminophen (Paracetamol) Metabolites Induce Vasodilation and Hypotension by Activating Kv7 Potassium Channels Directly and Indirectly Arteriosclerosis, Thrombosis, and Vascular Biology Acetaminophen metabolism