Reducing the effects of drug toxicity on glutathione metabolism ScienceDirect Early life acetaminophen exposure, glutathione S transferase genes, and development of adolescent asthma in a high risk birth cohort Journal of Allergy and Clinical Immunology About Acetaminophen Overdose About Acetaminophen Overdose Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize Acetylcysteine for Acetaminophen Poisoning New England Journal of Medicine