Vape vs Cigarette Nicotine: How Many 5% Vape Puffs Equal One Cig? One Juul pod contains the equivalent nicotine of 20 cigarettes a highly addictive amount. Today, some e cigs can contain more nicotine than *200 cigarettes.* Join us in sending a message to How many cigarettes equal one vape? 1 electronic cigarette pod is roughly equal to 20 cigarettes' worth of nicotine, or 200 puffs. That's a lot! Make the choice not to let nicotine control your life. #EliminateTobacco and put What is one vape equivalent to 50 cigarettes? Freeton Premium Disposable E cigarette Brand Vape Puffs vs Cigarettes: A Nicotine Comparison Clutch Vape